Charlotte's 49ers ended a three-game losing streak, blowing past Tulane in the second half in the American Conference tournament Thursday.

Brock Purdy had another excellent day through the air, throwing for three touchdowns in leading the San Francisco 49ers to a convincing 27-14 victory over the Tampa Bay Buccaneers on Sunday. Purdy ...

Brandon Aiyuk scored the winning touchdown reception in overtime as the San Francisco 49ers rallied to beat the Cincinnati Bengals 26-23 in one of the most thrilling games of the season. Aiyuk ...

The San Francisco 49ers and Seattle Seahawks face off for the third time this season. They split the two meetings in the regular season with the road team coming out on top, and now a trip to the NFC ...

A trip to Mexico will mark the second of two international contests for the 49ers in 2026. They also face the Rams as the ...