The apicoplast is a relict, non-photosynthetic plastid found in apicomplexan parasites such as Plasmodium spp. It originated from a secondary eukaryote–eukaryote endosymbiosis and retains four ...

image: Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood, and intrinsic ...

Studies hint at new drug targets and suggest the modified parasites could be used as attenuated vaccine. Scientists claim to have identified the only compound that is essential for the Plasmodium ...

Unlike any structure found in human cells, the apicoplast is unique to apicomplexan parasites—a large group of single-celled organisms that includes Plasmodium, Toxoplasma gondii, and Babesia. This ...

Scientists may have found a critical weakness in Plasmodium falciparum, the parasite that causes malaria. Researchers say the discovery provides a promising target for new malaria therapies. The ...

Researchers led by teams at the University of California, Riverside (UCR), the University of California, Irvine, and the Yale School of Medicine have developed a compound that they found to be ...

By targeting the apicoplast's DNA synthesis and vesicular trafficking pathways, Trapicolast disrupts the parasite's ability to survive and reproduce, providing a robust defense against drug-resistant ...

Researchers studying the malaria parasite Plasmodium falciparum have discovered a previously unknown stage in its life cycle that appears to be crucial for reproduction. This is important because ...

Researchers studying the malaria parasite Plasmodium falciparum have discovered a previously unknown stage in its life cycle that appears to be crucial for reproduction. This is important because ...