A new study suggests the APOE2 longevity gene may protect the brain from Alzheimer's by helping neurons repair DNA damage and ...

A research team at the Brain Research Institute, Niigata University has found that APOE ε4, a genetic factor best known for ...

A new study published by the Alzheimer's Association links biological age measured through blood metabolites to increased all ...

The Alzheimer's risk gene APOE ε4 drives the aggressive, brain-wide Type 2 subtype of ALS, causing cognitive decline.

The APOE2 gene variant protects against Alzheimer's by enhancing DNA repair and preventing neuronal senescence.

Two rare mutations in the APOE gene ― APOE ε4 (R251G) and APOE ε3 (V236E) ― dramatically reduce the risk of developing Alzheimer's disease (AD), results of a large genetic association study show. APOE ...

In a recent article published in the Journal of Alzheimer’s & Dementia, researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs). This platform aims to inform ...

A flurry of recent studies implicating microglia as key players in neurodegenerative diseases, particularly Alzheimer’s, has cued many labs to try to figure out how these cells function in health, and ...

ApoE research is not just about its three main alleles. You may have heard the words Christchurch and Jacksonville in connection with ApoE, but did you know that well over 100 variants have been ...

Nonetheless, smaller studies have generated some striking findings. For instance, the PPARγ agonist rosiglitazone (RSG) was efficacious only in ɛ4-negative patients, 12 making ɛ4 genotype a candidate ...