Cataplexy is a condition that brings on brief bouts of muscle weakness or paralysis. It can happen in people living with the sleep disorder narcolepsy. Some people have an episode of cataplexy just ...

Narcolepsy with cataplexy, now known as type 1 narcolepsy, is a chronic neurological disorder that affects a person’s sleep-wake cycle and involves muscle weakness. The condition can cause a person to ...

Cataplexy is a sudden, brief loss of voluntary muscle tone triggered by strong emotions such as laughter, excitement, anger or fear. There is a strong association between cataplexy and narcolepsy, a ...

Cataplexy is a sudden episode of muscle weakness that occurs while fully aware and conscious. It can be triggered by emotional events, such as laughing, crying or fear, and is usually transient in ...

Pitolisant is now the only treatment option not scheduled as a controlled substance that is indicated for both excessive daytime sleepiness and cataplexy in pediatric and adult patients. The Food and ...

The approval was based on data from two phase 3 trials (HARMONY CTP and HARMONY 1) that evaluated the efficacy and safety of pitolisant for the treatment of cataplexy. The Food and Drug Administration ...

Type 2 narcolepsy features excessive daytime sleepiness (EDS) without cataplexy — the sudden loss of muscle tone triggered by emotions that defines type 1. Symptoms are generally milder than type 1.

SAN DIEGO — The investigational drug AXS-12 (reboxetine, Axsome Therapeutics) is safe and effective for the treatment of cataplexy (emotionally induced muscle weakness) and excessive daytime ...

Cataplexy, or sudden muscle weakness that can resemble fainting, may be prompted by strong emotions. This symptom isn't serious and mostly occurs with narcolepsy type one — otherwise, it's very rare.

One cheerleader is rewriting what determination looks like by pushing boundaries on the mat while managing a chronic sleep disorder Courtesy of Rylie Shaw Rylie Shaw is a championship-winning athlete ...

Orexins are neurotransmitters, which are chemicals in your brain that send messages from one neuron (a nerve cell) to another. When you’re awake, those neurons send out orexins. The orexins then bind ...

Cataplexy is a sudden loss of muscle tone. It’s associated with a condition called narcolepsy. It can look like a seizure, but it’s not. Treatment involves medication and lifestyle changes. Cataplexy ...