More than 30 years after the direct connection was established between the molecular machinery controlling cell division and ...

The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...

Researchers at Lund University have shown that pancreatic cancer cells engineered to survive detachment consistently switch ...

In a tale of identities as divergent as "The Prince and the Pauper," a well-known cancer-causing gene also influences cells in a zombie-like state meant to prevent cancer. Scientists at Sanford ...

In eukaryotes, the cell cycle consists of four discrete phases: G 1, S, G 2, and M. The S or synthesis phase is when DNA replication occurs, and the M or mitosis phase is when the cell actually ...

An analysis of nearly half a million cells from dozens of patients' tumors reveals how cancer cells continuously reshape ...

New research shows that blocking the CXCL12/CXCR4 signaling axis in ovarian cancer cells produces a paradoxical biphasic ...

Cell cycle plasticity is a fundamental hallmark of every tumor, playing a crucial role in cancer initiation, progression, and treatment. We developed cell cycle mapping, a technological platform that ...

CAF Crosstalk to Reprogram the tumor microenvironment (TME). Ctx-ETAC suppresses EV secretion, disrupts cancer-CAF ...

Circadian rhythms influence not only sleep and metabolism but also the ability of cancer cells to invade, survive in blood, ...

In 2016, Colinda Scheele, a cancer biologist at Catholic University Leuven, was studying how chemotherapy affects breast cancer cells in mice. However, she observed an inconsistency: Some cell ...