An international research team led jointly by the University Medical Center Göttingen (UMG), the University of Göttingen and ...

DEK is a highly conserved chromatin-associated oncoprotein with important roles in chromatin biology and disease. First identified in 1992 as part of a DEK–NUP214 (nucleoporin 214) fusion resulting ...

Most if not all organs in mammals have adult stem cells that have some capacity to make and repair tissues throughout the lifetime of the organism. To understand how stem cells achieve these functions ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...

Parkinson's disease (PD) is a disabling neurodegenerative disease that affects approximately 10 million people worldwide, with numbers steadily increasing. Symptoms include tremors, difficulties with ...

Scientists in Zurich have shown that stem cell transplants can reverse stroke damage by regenerating neurons, restoring motor functions, and even repairing blood vessels. The breakthrough not only ...

A new study led by Hartmut Geiger at the University of Ulm, Germany, and Yi Zheng and Kodandaramireddy Nalapareddy, Cincinnati Children's Hospital Medical Center (CCHMC), USA reveals that age-related ...

As blood stem cells age, their lysosomes become overactive and damaged, triggering inflammation and weakening the body’s ability to regenerate healthy blood and immune cells. By calming this cellular ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...