Cholesterol transport underpins the development and prevention of cardiovascular disease through a finely tuned network of lipid carriers, enzymes and cellular transporters. Low-density lipoproteins ...

Every day, your liver assembles billions of tiny cholesterol-carrying particles and ships them into your blood. How many it ...

Researchers suggest targeting mTOR activity in aggressive cancers by blocking cholesterol sensing may represent a promising ...

Background: Disturbances in lipid homeostasis and myelination have been proposed in the pathophysiology of schizophrenia and bipolar disorder. We have previously shown that several antipsychotic and ...

Cholesterol is an essential component of living organisms, but the mechanisms that transport cholesterol inside the cell are poorly understood. Researchers have identified RELCH, a tethering protein ...

Cholesterol is indispensable for fetal development, serving as a structural component of cell membranes and a precursor for steroid hormone synthesis. Maternal-to-fetal transfer occurs across the ...

Kinases that shuttle cholesterol within tumor cells help fuel growth. Blocking these enzymes may starve cancer cells, ...

A team of the University of Barcelona (UB) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) identified a mechanism involved in the movement of cholesterol inside the cells. The study ...

A single enzyme in the brain quietly dismantles the receptors neurons need to clear amyloid, the toxic protein that ...

A study has identified a key disruption in cholesterol transport to the brain in patients with Alzheimer's disease. The findings suggest that the lipoproteins in the cerebrospinal fluid of patients ...

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for ...