In human cells, lengthy strands of DNA have to be carefully organized and compacted so they'll fit into the nucleus; our genome is arranged into chromosomes that have to be duplicated each time a cell ...

Female mammals carry two X chromosomes, while male mammals carry an X and a Y chromosome. The X chromosome carries a thousand genes, so in females, one of the X chromosomes must be silenced to avoid ...

Here, we discuss the recently proposed oncogene-induced mitotic stress model that provides a mechanistic framework for the long-standing paradox that the majority of cancers are aneuploid, whereas ...

Once in every cell cycle microtubules become organized into a bipolar spindle that segregates the replicated chromosomes to the two daughter cells 1,2. Two models, which are not mutually exclusive, ...

In a biological first, an international team has inserted a man-made chromosome into brewer's yeast, producing a life form that thrives and successfully passes the designer genes on to its offspring.