A 3:1 mixture of ethyl acetate and ethanol, for example, can be an effective replacement for DCM in some column chromatography applications, but may not be an effective “catch-all” extraction solvent ...

DCM is immiscible, meaning it doesn't dissolve in water, and it evaporates easily, simplifying the process of separating and extracting compounds. Unlike many other solvents, it won't catch on fire, ...

Dichloromethane, a solvent widely used in organic chemistry and manufacturing, is what chemistry Prof. Bryan Hunter calls a “Goldilocks of the solvents.” DCM is particularly useful as a reaction ...

The EPA’s 2024 final risk management rule on dichloromethane (DCM) prohibits the distribution and most uses of DCM, aiming to minimize harmful health effects of the commonly used solvent. Adjusting to ...

Across teaching and research labs, chemists are rethinking solvent choices to protect health and the planet. From replacing carcinogenic dichloromethane to reusing ethyl acetate, greener practices are ...