Investigators often work with complex nucleic acid samples in procedures such as amplification, renaturation, cDNA synthesis and normalization, sonication, digestion, nicking, labeling and ...

The main goal of the molecular diagnosis of hereditary diseases is the identification of disease-causing mutations with a view to detecting carrier individuals who may benefit from early diagnosis, ...

In this article, we will consider how agarose gel electrophoresis works, how it can be interpreted and some of its purposes. Electrophoresis is a technique that uses electrical current to separate DNA ...

Pulsed-field gel electrophoresis (PFGE), or clamped homogeneous electrical field electrophoresis (CHEF), is a novel gel electrophoresis type for the separation of DNA macromolecules. This is ...

Before you can embark on one of the many applications involving genomic DNA (gDNA), it is important to assess the quality of your samples, especially if these samples could have been exposed to ...