Lymphocyte development relies on the deliberate induction and precise repair of DNA double-strand breaks (DSBs) to generate the diverse repertoire of antigen receptors that underpin adaptive immunity.
The transcription factors encoded by the E2A gene are critical for the initiation of B cell development in the bone marrow. In the early Edition of the Proceedings of the National Academy of Science s ...
In a recent study posted to the bioRxiv* preprint server, researchers evaluated the BNT162b2 coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine (antigen)-specific immune ...
Atypical lymphocytes are types of white blood cells that a person’s immune system produces. They help fight infections and diseases. High levels of atypical lymphocytes may indicate health issues.
Effect of BL-8040, high-affinity CXCR4 antagonist, on T-cell infiltration, tumor growth, and synergy with immunomodulatory agents. This is an ASCO Meeting Abstract from the 2017 ASCO Annual Meeting I.