Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, ...

E3 ligases are enzymes that act as molecular "broker" by binding specific target proteins and coordinating the transfer of ubiquitin from an E2 enzyme. As an E3 ligase recognizes only a restricted set ...

This article and associated images are based on a poster originally authored by Ashleigh Hill, Marie-Louise Francis, Viktoria Brachmaier, Egle Vaitone, Rachel Forfar and Sandra Kuemper and presented ...

Cells have a remarkable housekeeping system: Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery ...

Thymus is the key organ for development and maturation of T lymphocytes. The dysfunction of thymus leads to decreased immunity or autoimmune diseases. T cells can be divided intoαβ T cells and γδ T ...

Within the bustling metropolis of your cells, amidst the teeming throngs of proteins, reside the E3 ligases – the silent guardians of cellular order. These are not your average bouncers, but the ...

Data shows iberdomide combination therapy delivers progression free survival and safety in relapsed and refractory multiple ...

This is a preview. Log in through your library . Abstract Germline specification is the first step during sexual and apomictic plant reproduction, and takes place in the nucellus of the ovule, a ...

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with precision.