Female fertility depends on the successful growth and maturation of eggs (oocytes) within ovarian follicles. Within these ...

Female fertility depends on the successful growth and maturation of eggs (oocytes) within ovarian follicles. Within these ...

In vitro ovarian follicle development encompasses the isolation, culture and maturation of ovarian follicles outside the body, with the ultimate aim of generating developmentally competent oocytes.

A new study reveals that microtubules, previously overlooked in ovarian follicles, are vital for egg cell communication and ovulation. Camsap3 loss impaired follicle development and caused infertility ...

The preantral phase of ovarian folliculogenesis encompasses the period from primordial follicle activation through secondary follicle growth, before antrum formation. During this stage, dormant ...

A recent study published in Nature Communications by researchers at Karolinska Institutet offers new insights into the development of ovarian follicles, which are vital for female fertility as they ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

A multi-institutional team of ovarian biologists and other reproductive specialists reports that putting an oocyte from an older mouse into the follicle of a young mouse can rejuvenate the oocyte, ...

A picture of a mouse MII stage eggs with the location of chromosomes (green) and the distribution of the histone modification H3K4me3 (purple). The team confirmed that H3K4me3 was significantly ...

Study: Explainable artificial intelligence to identify follicles that optimize clinical outcomes during assisted conception. Image Credit: Corona Borealis Studio / Shutterstock.com A recent Nature ...

Pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) recruit immune cells, intensify oxidative stress, and accelerate granulosa-cell apoptosis; IL-6 upregulates Bax and caspase-3, reducing follicular ...