This new article publication from Acta Pharmaceutica Sinica B, discusses how an innovative and stable mRNA-LNP microneedle vaccine elicits humoral and multifunctional cellular immune responses. During ...
The pGen-SHM plot combines BCR generation probability and somatic hypermutation to track humoral immune recovery after stem cell transplantation. The approach has revealed distinct maturation patterns ...
Single-cell transcriptomics across multiple COVID-19 cohorts reveals that peripheral B cell dysregulation, marked by plasmablast expansion and naive B cell depletion, is associated with post-COVID ...
Clonal B-cell–mediated hypogammaglobulinemia is common (up to 85%) and can coexist with qualitative immune defects that blunt vaccine responses and protection against encapsulated bacteria. T-cell ...