A recent British Journal of Cancer study investigated how cancer stem cells (CSCs) induce resistance to chimeric antigen receptor T (CAR-T) cell therapy. Furthermore, the effect of Interleukin-24 ...
A Novel Anti-Apoptosis Gene: Re-expression of Survivin Messenger RNA as a Prognosis Marker in Non–Small-Cell Lung Cancers PURPOSE: To determine the short- and long-term efficacy and toxicity of the ...
Lebrikizumab, a high-affinity IgG4 monoclonal antibody targeting interleukin-13, prevents the formation of the interleukin-4Rα–interleukin-13Rα1 heterodimer receptor signaling complex. We conducted ...
Acute kidney injury (AKI) is a severe renal disorder affecting approximately 10%–15% of hospitalized patients and up to 50% in intensive care units (ICUs). Its pathogenesis involves complex ...
Interleukin-6 (IL-6) is a pleiotropic cytokine that may play a role in the regulation of various aspects of the immune response, inflammation, hematopoiesis, and bone metabolism. IL-6 acts by binding ...
Osteoarthritis is increasingly recognised as a disorder with both mechanical and inflammatory components, in which interleukin-1 (IL-1) plays a central role by driving cartilage degradation, synovial ...
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