Plasmodium falciparum exhibits a tightly orchestrated intraerythrocytic cycle that aligns with host circadian rhythms, optimising parasite replication, transmission potential and evasion of immune ...

image: Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood, and intrinsic ...

The mosquito-borne infectious disease malaria resulted in about 241 million clinical episodes and 627,000 deaths in 2020. In young children and pregnant women living in areas where the disease is ...

Comprehensive genetic mapping of Plasmodium knowlesi, a zoonotic parasite that causes malaria, has revealed the genes required for malaria infection of the blood, and those driving drug resistance. By ...

Researchers studying the malaria parasite Plasmodium falciparum have discovered a previously unknown stage in its life cycle that appears to be crucial for reproduction. This is important because ...

Natural malaria infections have been genetically analysed at a higher resolution than ever before, giving insights that could help understand and block transmission. For the first time, the ...

Malaria is caused by a eukaryotic microbe of the Plasmodium genus, and is responsible for more deaths than all other parasitic diseases combined. In order to transmit from the human host to the ...