Figure 1: Nondisjunction causes near-diploid aneuploidy, not cytokinesis failure, in primary cells. If nondisjunction were to give rise to binucleation and if binucleate cells were to survive as well ...

Figure 1: Chromosome mis-segregation occurs at high frequency in spontaneously arising binucleated cells. Figure 2: Nondisjunction occurs with high frequency in cells that become binucleated by furrow ...

STUDIES of human chromosomes have been greatly facilitated by the development of newer technics, particularly peripheral blood leukocyte culture. 1–3 Many abnormalities have been described, most of ...

A nondisjunction and chromosome breakage screening system devised by Craymer and modified in our laboratory, involves an X;Y translocation with the short arm of the Y ( Y S), marked with the wild type ...

Chromosome nondisjunction lands a heavy blow on the chin of humanity. The improper segregation of chromosomes during meiosis leads to chromosomally unbalanced eggs or sperm. If these gametes ...

Changes in either chromosome structure or number can occur during cell division. Each human has 46 chromosomes, 22 pairs of autosomes and 1 pair of sex chromosomes (XX: female or XY: male). During ...