Plasmodium falciparum exhibits a tightly orchestrated intraerythrocytic cycle that aligns with host circadian rhythms, optimising parasite replication, transmission potential and evasion of immune ...

The mosquito-borne infectious disease malaria resulted in about 241 million clinical episodes and 627,000 deaths in 2020. In young children and pregnant women living in areas where the disease is ...

Researchers studying the malaria parasite Plasmodium falciparum have discovered a previously unknown stage in its life cycle that appears to be crucial for reproduction. This is important because ...

Findings can open up new avenues for targeted approaches toward therapeutic strategies against the malaria-causing P. falciparum that are aimed at stopping the parasite's life cycle progression and ...

Interaction between LFA-1 on natural killer cells and GBP-130 on infected erythrocytes enables immune recognition and killing of Plasmodium falciparum-infected red blood cells.

image: Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood, and intrinsic ...

Malaria is a life-threatening disease that is caused by unicellular eukaryotic parasites of the genus Plasmodium, with P. falciparum being responsible for the most severe form of human malaria. In the ...