These images captured using high-speed atomic force microscopy, represent the snapshots of the protein substrate getting translocated through the SecYEG-SecA complex. The left image indicates the ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
Recent advances in single-molecule technologies are transforming the field of protein analysis. Solid-state nanopores provide an effective method to linearize and thread full-length proteins in a ...