Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the “powerhouses” of ...
Pyruvate kinase occupies a central role in glycolysis, catalysing the conversion of phosphoenolpyruvate to pyruvate with concomitant ATP generation. Its activity is finely tuned by allosteric ...