In a new study published in the journal Nature Genetics, Haolong Li, PhD, a researcher at Fred Hutch Cancer Center, and colleagues developed a way to monitor androgen receptor levels inside living ...

Taste, pain, or response to stress — nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University of ...

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), ...

Understanding the thermodynamic basis of ligand recognition by G-protein-coupled receptors (GPCRs), especially in terms of ...

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new ...

Chimeric antigen receptor (CAR) T cell therapy, a type of immunotherapy that leverages the immune system to combat diseases, ...

The amount of each of the more than a thousand different glycoproteins in your blood varies widely with the 10 most abundant glycoproteins accounting for 90 percent of the total mass. Finding a ...

Scientists from the Riken Center for Sustainable Resource Science (CSRS) in Japan have identified an ancient protein that, with modifications, could confer broad-spectrum protection for plants against ...

Finding the right taste to send mosquitoes packing could save hundreds of thousands of lives. (Photo by Егор Камелев on Unsplash) Mosquitoes are the most ...

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...