The immune system has evolved to mount immune responses against foreign pathogens and to remain silent against self-antigens. A balance between immunity and tolerance is required as any disturbance ...

This Collection supports and amplifies research related to SDG 3: Good Health & Wellbeing. B cells are no longer viewed solely as antibody-producing cells, but as multifunctional immune regulators ...

The 2025 Nobel Prize in Physiology or Medicine was awarded earlier this month to immunologists Mary E. Brunkow (Institute for Systems Biology, Seattle), Fred Ramsdell (Sonoma Biotherapeutics, San ...

The Nobel-prize season always kicks off with the award for physiology or medicine, which highlights work in fields such as genetics, cell biology and evolution. This year’s award went to three ...

Findings from a new study led by scientists at Stanford University School of Medicine and their colleagues elsewhere show that a single signaling pathway controls whether immune cells attack or ...

Scientists from the Institute of Molecular Genetics of the Czech Academy of Sciences, in collaboration with the Faculty of Science at Charles University, have uncovered a completely new role for the ...

When Francisco Leon talks about the medical science behind the biotech company he founded in 2023, it sounds like something out of a movie. The company, Tolerance Bio, focuses on preserving the body’s ...

I have studied my own health and the health of 1000 other autoimmune-diagnosed women: Self-abandoning “good girl” roles may ...

Every day, your immune system performs a delicate balancing act, defending you from thousands of pathogens that cause disease while sparing your body's own healthy cells. This careful equilibrium is ...