Tipoff from State Farm Arena in Atlanta is set for 12:30 p.m. ET. The Red Storm are 2.5-point favorites, while the over/under is 155.5 in the latest Kentucky vs. St. John's odds. Before making any St. John's vs. Kentucky picks, check out the men's college basketball predictions and betting advice from the SportsLine Projection Model.

A projected NBA lottery pick, Jayden Quaintance had a major impact for the UK basketball team in its first win over a ranked team.

The Kentucky Wildcats square off against the No. 22 St. John's Red Storm at State Farm Arena in Atlanta, Georgia. The teams meet Saturday for the first time this season.

Quaintance practiced in full this week, but his status for Saturday is still up in the air. Even if he plays just 10 minutes, that's an enormous boon for a Kentucky front-line that will be tested by Hopkins, Zuby Ejiofor, Dillon Mitchell and Ruben Prey.

The Kentucky Wildcats will take on the St. John’s Red Storm on Saturday afternoon in the CBS Sports Classic in Atlanta. Game time is set for 12:30 PM ET on CBS.

St. John’s has lost its four biggest tests of non-conference play, previously dropping ranked matchups against Alabama, Iowa State and Auburn.

Mark Pope battles his former coach, Rick Pitino, as Kentucky faces St. John's. Here's everything you need to know about the showdown.

By the midway point of the second half, the result wasn’t in doubt. St. John’s was headed to another dismal defeat, a 78-66 loss to Kentucky that will no doubt knock them from the Associated Press top-25 for the first time this year.

What channel is Kentucky basketball vs St. John's on today? How to watch UK vs St. John's, game time, TV schedule, livestream info, more.

BOTTOM LINE: No. 22 St. John’s and Kentucky square off in Atlanta, Georgia. The Wildcats have a 7-4 record in non-conference games. Kentucky is sixth in the SEC with 27.5 defensive rebounds per game led by Malachi Moreno averaging 4.3.