The National Weather Service in Cleveland has issued a Winter Storm Watch for Lake, Geauga and Ashtabula counties for Thursday and Friday. Significant snowfall is likely.

A major winter storm is set to hit multiple states over the Thanksgiving holiday period. Follow Newsweek's live blog.

Coast-to-coast storm systems could disrupt Thanksgiving travel plans for millions of Americans this week, forecasters say. Here's what to expect.

Forecasters say there’s a high level of uncertainty over how the storm system will develop, how strong it will be and where it will track.

Residents in several states across the U.S. have been issued winter storm warnings, which may bring up to 20 inches of snow to some areas, which, according to the National Weather Service (NWS), could make “travel treacherous and potentially life-threatening” across Wednesday and Thursday, and, for some, even through to Saturday.

A winter storm warning and winter weather advisory are in effect in West Michigan until 7 p.m. Thursday. In South Haven, gusts were measured at 53 mph before noon Wednesday. By late afternoon, gusts in the same area were recorded at 56 MPH.

The metro is in line for 1 to 3 inches Tuesday night into Wednesday; up to 4 inches further north, the National Weather Service said.