In vitro fertilization is clearly a successful technology, although it remains experimental; the safety and efficacy of new methods and reagents can be difficult to assess. And “traditional ...

The authors describe the implications of the Affordable Care Act for safety-net health systems and how hospital-based safety-net care systems are responding to health care reform.

Children born to women who carry pathogenic variants in mitochondrial DNA (mtDNA) are at risk for a range of clinical syndromes collectively known as mtDNA disease. Mitochondrial donation by pronuc ...

Pathogenic variants in mitochondrial DNA (mtDNA) are a common cause of severe, often fatal, inherited metabolic disease. A reproductive care pathway was implemented to provide women carrying pathog ...

Sarcoidosis, a granulomatous disease that affects the lungs and other organs, has a variable course. Although spontaneous resolution of sarcoidosis occurs in some patients, half the patients with s ...

A 68-year-old man with type 2 diabetes presented with a 3-year history of hardening of the skin on his neck and upper back.

A 29-year-old woman presented 4 months after a vaginal delivery with a new mass protruding from her vaginal canal. A diagnosis of Gartner’s duct cyst was made histologically after resection of ...

In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone ...

AI mammography aids are being sold as additions to mammography screening, with direct-to-consumer marketing touting improved cancer-detection rates, despite a lack of evidence of clinical effective ...

When his mother is diagnosed with what medicine calls “heart failure,” an epidemiologist identifies harmful flaws in both the term and communication with patients and families.

To the Editor: In the POPular PAUSE TAVI (Periprocedural Continuation versus Interruption of Oral Anticoagulant Drugs during Transcatheter Aortic Valve Implantation) trial, van Ginkel et al. (Jan ...

To the Editor: In the phase 3 GRADUATE trials of gantenerumab for early Alzheimer’s disease reported by Bateman et al. (Nov. 16 issue),1 participants receiving gantenerumab had a greater ...