Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

The Arizona Cardinals suffered another blowout loss. On Sunday at State Farm Stadium, they gave up a 98-yard kickoff return ...

The 49ers are now 9-4, going into the bye week with an absolutely depleted defensive roster. Even when considering the Super Bowl seasons, this may be Kyle Shanahan’s most impressive year as head ...

The Arizona Cardinals were destroyed by the Seahawks last week but they have a chance to get back on track in Week 11, with ...

49ers quarterback Brock Purdy threw three touchdown passes in his first game since Week 4, and running back Christian ...

The San Francisco 49ers dominated their Week 11 matchup as the Arizona Cardinals were exposed once again.

The Arizona Cardinals are back in action in Week 11, facing the San Francisco 49ers for the second time this season. The 6-4 ...

USA Today's NFL experts make their picks for a Week 11 showdown between the Arizona Cardinals and San Francisco 49ers ...

It wasn't an easy outing for the San Francisco 49ers in the initial matchup with the Arizona Cardinals. Their rematch with Arizona in Week 11 could very well pl ...

The San Francisco 49ers defeated the Arizona Cardinals on Sunday. Here's who had the best and worst days, according to Pro ...

The 49ers (6-4) visit the Cardinals (3-6) at State Farm Stadium (Fox, 1:05 p.m.) with quarterback Brock Purdy (toe) and wide ...

Brock Purdy passed for 200 yards and three touchdowns in his first game since Sept. 28, Christian McCaffrey scored three touchdowns and the San Francisco 49ers beat the error-prone Arizona Cardinals ...