Wallerian degeneration (WD) after ischaemic stroke is a well known phenomenon following a stereotypical time course. Whereas conventional magnetic resonance imaging fails to detect signal intensity ...

Objective To assess the current use of glucocorticoids (GCs) in Duchenne muscular dystrophy in the UK, and compare the benefits and the adverse events of daily versus intermittent prednisolone ...

Influential models based on an increasing body of neuroimaging evidence propose that insular cortex integrates cognitive, affective, sensory and autonomic information to create a consciously perceived ...

Background Conversion disorder is largely managed by neurologists, for whom it presents great challenges to understanding and management. This study aimed to quantify these challenges, examining how ...

OBJECTIVE Necropsy confirmed clinical diagnostic accuracy for Alzheimer’s disease is claimed to exceed 90%. This figure contains two fallacies; it includes cases in which Alzheimer’s disease exists ...

Hashimoto’s encephalopathy is a steroid responsive disorder characterised by high titres of anti-thyroid antibodies and manifesting as sub-acute onset of confusion, episodes of myoclonus, seizures, ...

The word hippocampus comes from late Latin: hippocampus, derived from the Greek words for a horse+sea monster. In mythology it was a sea horse, having two forefeet, with the body ending in a dolphin's ...

Background: The 39 item Parkinson’s disease questionnaire (PDQ-39) is the most widely used patient reported rating scale in Parkinson’s disease. However, several fundamental measurement assumptions ...

Objectives/Aims The abuse of nitrous oxide (N2O) may be increasing globally and users and clinicians may not be aware of harms. We highlight these potential harms through the case of a woman treated ...

Background: Biomarkers of stroke are an evolving field of clinical research. A serum marker which can differentiate between haemorrhagic and ischaemic stroke in the very early phase would help to ...

Background Deep brain stimulation (DBS) improves motor symptoms in Parkinson's disease (PD), but questions remain regarding neuropsychological decrements sometimes associated with this treatment, ...