Blood tests for Alzheimer’s disease are rapidly transforming the way clinicians diagnose the disease. Still, some scientists urge caution when interpreting results, arguing that the meaning of a ...

Rarely do scientists discover a new pathogenic mutation for a sporadic disease. Even less often do they find one that explains half the cases. Pinning disease on a dinucleotide expansion? That’s a new ...

Scientists continue to look for new ways to target sticky amyloid plaques in the brain. The approved immunotherapies have well-known limitations. In the March 5 Science, Marco Colonna and colleagues ...

Circular RNAs are the byproducts of aberrant “backsplicing.” They accumulate and cause problems in the brain with age. According to a study published March 5 in Molecular Cell, ribonuclease κ—an ...

The gene PSEN2 encodes presenilin-2, a subunit of γ-secretase, the aspartyl protease responsible for Aβ generation. Missense mutations in PSEN2 are a rare cause of early onset Alzheimer's disease.

Professional Information University of South Florida Comments Could Tau Explain the Link Between Pneumonia and Dementia? 06 Mar 2026 ...

The network provides high-quality brain tissue to scientists and clinicians and supports major initiatives on research into neurological disorders, including the aims of the Ministerial Action Group ...