Oncology Nurse Advisor

Metformin Reduces BM Fibrosis and JAK-STAT Signaling in PMF

In the open-label FIBROMET trial, metformin treatment was associated with reductions in bone marrow fibrosis and downregulation of key oncogenic signaling pathways in patients wit ...
MedPage Today

JAK Inhibitor Therapy for Alopecia Areata in Black Patients

A new study highlights the value of JAK inhibitors (JAKi) for managing alopecia areata (AA) in Black and African American patient populations. The analysis appears in the International Journal of ...
The Hill

FDA proposes new treatment approval pathway for ultrarare diseases

The Food and Drug Administration (FDA) announced a new proposal Monday for flexible drug approval pathway treatments addressing ultrarare diseases. The FDA unveiled draft guidance on a proposed ...
STAT

FDA unveils rules for bespoke gene therapies, predicting flood of rare disease applications

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason ...
Healio

JAK inhibitors ‘should be standard of care’ when treating alopecia

Please provide your email address to receive an email when new articles are posted on . Most people with alopecia are good candidates for JAK inhibitor therapy with proper counseling and monitoring.
STAT

FDA’s new ‘plausible mechanism pathway’ for personalized gene editing raises concerns

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason ...
Seeking Alpha

Ontario Pioneers Access to Treatment for Severe Alopecia Areata with Lilly's Olumiant®

TORONTO, Jan. 14, 2026 /CNW/ - Eli Lilly Canada Inc. ("Lilly") announced today that Ontario leads the way as the first province to add Olumiant ® for severe alopecia areata to its public drug ...
Benzinga.com

STAT+: Makary, Prasad outline pathway for bespoke gene therapy

FDA Commissioner Marty Makary and biologics chief Vinay Prasad have sketched out the agency’s first real blueprint for approving personalized gene-editing therapies, STAT’s Jason Mast reports. It’s a ...
The American Journal of Managed Care

Ritlecitinib Shows Significant Reduction in Alopecia Areata Psychosocial Burden

Ritlecitinib effectively reduces psychosocial burden in severe alopecia areata, beyond hair regrowth benefits. Significant improvements in emotional symptoms and activity limitations were observed ...
EurekAlert!

Decoding sepsis: Unraveling key signaling pathways for targeted therapies

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...
Sports Illustrated

Aston Martin Announces Promotion For American F1 Hopeful Jak Crawford

Aston Martin has announced that American Formula 2 star Jak Crawford will be the team's third driver for the 2026 Formula 1 season. Crawford will continue the development role he has taken as part of ...