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Prevalence and outcomes of anxiety and depression in fibrotic interstitial lung disease: a registry-based analysis

Anxiety and/or depression are common in fibrotic interstitial lung disease (ILD) but with unclear treatment implications. A prospective multicentre registry of 4009 patients was used to evaluate the ...
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Newborn with severe unresponsive hypoxic respiratory failure

A full-term male infant (39+4 weeks, 4125 g) was born following an uncomplicated pregnancy and delivery. Apgar scores were 9 ...
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Impact of a national mesothelioma network on outcomes including survival

Introduction Equitable delivery of high-quality care is challenging in mesothelioma. Previous UK audits report variable practice and outcomes. The Scottish Mesothelioma Network was launched in April ...
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Circulating CTHRC1 levels are associated with IPF disease severity and survival

Introduction Idiopathic pulmonary fibrosis (IPF) is a disease of high morbidity and mortality. We previously identified a novel subset of pathological fibroblasts, characterised by CTHRC1 expression, ...
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Beyond bronchopulmonary dysplasia: early-life determinants and divergent lung function trajectories of prematurity-associated lung disease

Respiratory follow-up of children and adults born prematurely thus far has largely focused on those with the diagnostic label of bronchopulmonary dysplasia (BPD) which is assigned early in life.1 ...
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CXCL11: the other side of the chemokine in influenza A induced COPD exacerbations

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
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Association between overuse of short-acting β2-agonists and the risk of major adverse cardiovascular events among patients with asthma

Background Short-acting β2-agonist (SABA) overuse is associated with increased asthma exacerbations and mortality, yet its impact on cardiovascular disease remains unclear. We investigate the ...
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Aetiological role of viral and bacterial infections in acute adult lower respiratory tract infection (LRTI) in primary care

2 Department of Thoracic Medicine, Royal Free and University College Medical School, University College London, UK 3 Centre for Medical Microbiology, Royal Free and University College Medical School, ...
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S90 FRONTIER-3: a randomized, phase 2a study to evaluate the efficacy and safety of tozorakimab (an anti-interleukin-33 monoclonal antibody) in early-onset asthma

2 Research and Early Development, Respiratory and Immunology, BioPharmaceuticals RandD, AstraZeneca, Cambridge, UK 3 Respiratory and Immunology, Biometrics and Statistical Innovation, Late Respiratory ...
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Ambient PM2.5 exposure and hospital cost and length of hospital stay for respiratory diseases in 11 cities in Shanxi Province, China

Background Few studies have examined the effects of ambient particulate matter with an aerodynamic diameter less than or equal to 2.5 μm (PM2.5) on hospital cost and length of hospital stay for ...
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P205 Real world outcomes of Tezepelumab in obese and non-obese severe asthmatics

Introduction Obese patients with severe asthma have a distinct clinical phenotype. These patients are more likely to have low T2 biomarkers (T2low) so are less likely to meet criteria to be treated ...
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A child chronic cough-specific quality of life measure: development and validation

2 Qld Children's Respiratory Centre and Qld Children's Medical Research Institute, Royal Children's Hospital, Queensland University of Technology, Brisbane, Australia Background Quality of life (QoL) ...