PDB-101: Molecule of the Month: SARS-CoV-2 Spike
Spike protein from SARS-CoV, with one receptor binding domain (RBD) in the up position, and a closed conformation of the SARS-CoV-2 spike. The S1 fragment is shown in magenta and the S2 fragment …
5DO2: Complex structure of MERS-RBD bound with 4C2 antibody
Sep 10, 2015 · Both mAbs potently bind to MERS-RBD and block virus entry in vitro with high efficacy. We further investigated their mechanisms of neutralization by crystallizing the complex between the …
8HES: Crystal structure of SARS-CoV-2 RBD and NIV-10 complex
Nov 8, 2022 · 8HES | pdb_00008hes Crystal structure of SARS-CoV-2 RBD and NIV-10 complex PDB DOI: https://doi.org/10.2210/pdb8HES/pdb Classification: VIRAL PROTEIN/IMMUNE SYSTEM …
RCSB PDB - 7UB0: SARS-CoV-2 Omicron-BA.2 3-RBD down Spike …
Mar 14, 2022 · BA.2 receptor-binding domain (RBD) mutations induce remodeling of the RBD structure, resulting in tighter packing and improved thermostability. Interprotomer RBD interactions are …
RCSB PDB - 8ZER: Crystal structure of the complex of Wuhan SARS …
May 6, 2024 · Here we report on the successful crystal structure determination of the RBD:P2C5 complex at 3.1 Å, which revealed the intricate protein-protein interface, sterically occluding full ACE2 …
7VOA: Crystal structure of SARS-CoV-2 RBD in complex with aRBD5
Oct 13, 2021 · In contrast, aRBD-5 and aRBD-7 bind to less-conserved RBD epitopes non-overlapping with the epitope of aRBD-2, and do not show apparent binding to the RBD of some variants. …
RCSB PDB - 8Z27: The structure of TGEV RBD and dog APN complex
Apr 12, 2024 · We identified R325 of dAPN as an important residue in the PDCoV RBD-dAPN interaction, and found the central role of Q746 and T749 in dAPN in the interaction with the TGEV RBD.
RCSB PDB - 8Q93: Crystal structure of the SARS-COV-2 RBD with ...
Aug 19, 2023 · We have previously developed highly potent single-domain (VHH) antibodies, also known as nanobodies, that target the Receptor Binding Domain (RBD) of the SARS-CoV-2 Spike …
RCSB PDB - 9IU1: Structure of SARS-CoV-2 JN.1 spike RBD in complex …
Jul 20, 2024 · The SARS-CoV-2 spike protein, crucial for cellular entry, binds to the ACE2 receptor exclusively when its receptor-binding domain (RBD) adopts the up-conformation.
RCSB PDB - 7R6X: SARS-CoV-2 spike receptor-binding domain (RBD) in ...
Jun 23, 2021 · These data highlight principles underlying variation in escape, breadth and potency among antibodies that target the RBD, and identify epitopes and features to prioritize for therapeutic …