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askfilo.com
A mutation has damaged the formation of oxaloacetate. What proc... | Filo
A mutation has damaged the formation of oxaloacetate. What proc... | Filo
5 months ago
Oxaloacetic acid Function
Leucovorin, also known as folinic acid, is a biologically active form of folate. Research has shown that some children on the autism spectrum produce antibodies that interfere with folate transport in the brain. In such cases, folinic acid may be one of the few forms capable of crossing the blood-brain barrier, helping to support healthy cognitive and neurological function. Clip snippet credit goes to: @mahaaction *The statements made in this video have not been evaluated by the Food and Drug Ad
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Vitamin B12 acts as a cofactor (helper molecule) for several essential enzymes. Without it, major cellular reactions slow down or malfunction — especially those involving DNA synthesis, methylation, and energy metabolism. ⸻ 🧬 1. DNA Synthesis & Cell Division • B12 is required for thymidine synthesis, a building block of DNA. • Works alongside folate (vitamin B9) — they are tightly linked. • When B12 is low, folate becomes “trapped” in an unusable form (the methyl trap), leading to impaired DNA
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Formation of Oxaloacetate in a Mitochondrion In the last reaction of the citric acid cycle, malate is dehydrogenated to regenerate the oxaloacetate necessary for the entry of acetyl-CoA into the cycle: L-Malate +NAD^+ ⟶ oxaloacetate +NADH+H^+ ΔG^'0=30.0 kJ / mol (a) Calculate the equilibrium constant for this reaction at 25^∘ C. (b) Because ΔG^'0 assumes a standard pH of 7 , the equilibrium constant calculated in (a) corresponds to Keq ^'=([ oxaloacetate ][NADH])/([ L-malate ][NAD^+]) The
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