🧬 This skull showcases a rare condition called Craniofrontonasal Syndrome, a developmental disorder that causes severe facial asymmetry. What makes it fascinating is that it breaks the rules of genetics, it’s linked to the X chromosome, yet females are more severely affected. That’s because of a process called X-inactivation, where one of the two X chromosomes in females shuts off randomly, leading to uneven expression of the gene mutation. This skull shows the classic features of the condition