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Three diets, forced to the exact same 10% weight loss, and the liver still picked a favorite. A new randomized trial in Cell Metabolism put ketogenic, Mediterranean, and very low fat plant forward diets head to head in adults with metabolically unhealthy obesity, matching everyone to about 10% weight loss. Muscle insulin sensitivity improved roughly 50% across the board, but the low carb arm showed 2 to 3 times greater improvement in liver insulin sensitivity, with bigger reductions in liver fat
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