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The clinical presentation (hypotonia, upslanting palpebral fissures, simian crease, and clinodactyly) is classic for Down syndrome (Trisomy 21). The correct answer is B) VSD (Ventricular Septal Defect). While an Atrioventricular Septal Defect (AVSD)—also known as an endocardial cushion defect—is the most characteristic cardiac lesion for ...
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